RO-3, CAS 1026582-88-6

Product Description: RO-3 is a potent, CNS-penetrant, and orally active P2X3 and P2X2/3 antagonist with pIC50s of 5.9 and 7.0 for human homomultimeric P2X3 and heteromultimeric P2X2/3 receptors, respectively. RO-3 shows selectivity for P2X3 and P2X2/3 over all other functional homomultimeric P2X receptors (IC50 >10?μM at P2X1,2,4,5,7)[1].

Applications: Neuroscience-Neuromodulation

Formula: C16H22N4O2

References: [1]Ford AP, et al. Purinoceptors as therapeutic targets for lower urinary tract dysfunction. Br J Pharmacol. 2006;147 Suppl 2(Suppl 2):S132-S143.

CAS Number: 1026582-88-6

Molecular Weight: 302.37

Compound Purity: 97.32

Research Area: Neurological Disease

Solubility: DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C)

Target: P2X Receptor

• SKU: MEXHY-19978-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-19978-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK