Ro 41-1049 (hydrochloride), CAS 127917-66-2

Product Description: Ro 41-1049 hydrochloride is a reversible and selective inhibitor of monoamine oxidase-A (MAO-A). An homogeneous population of high affinity binding sites for [3H]Ro 41-1049 is found in membrane preparations from human frontal cortex and placenta (Kd values of 16.5 and 64.4 nM, respectively)[1].

Applications: Neuroscience-Neuromodulation

Formula: C12H13ClFN3OS

References: [1]Cesura AM, et al. Characterization of the binding of [3H]Ro 41-1049 to the active site of human monoamine oxidase-A. Mol Pharmacol. 1990 Mar;37(3):358-66./[2]Brannan T, et al. Effect of a selective MAO-A inhibitor (Ro 41-1049) on striatal L-dopa and dopamine metabolism: an in vivo study. J Neural Transm Park Dis Dement Sect. 1994;8(1-2):99-105.

CAS Number: 127917-66-2

Molecular Weight: 301.77

Compound Purity: 99.96

Research Area: Neurological Disease

Solubility: DMSO : ≥ 32 mg/mL/H2O : 25 mg/mL (ultrasonic)

Target: Monoamine Oxidase

• SKU: MEXHY-100027A-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100027A-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK