RO 46-8443, CAS 175556-12-4

Description: RO 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. RO 46-8443 displays up to 2000-fold selectivity for ETB receptors both in terms of binding inhibitory potency and functional inhibition.

CAS Number: 175556-12-4

Formula: C31H35N3O8S

Molecular Weight: 609,69

References: Guimarães CL, Trentin PG, Rae GA. Endothelin ET(B) receptor-mediated mechanisms involved in oleic acid-induced acute lung injury in mice. Clin Sci (Lond). 2002 Aug;103 Suppl 48:340S-344S.

• SKU: TGMT3474-2mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T3474-2mg
• Package Unit: 2 mg
• Quantity Unit: STK