Rociletinib, CAS 1374640-70-6

Product Description: Rociletinib (CO-1686) is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively.

Applications: Cancer-Kinase/protease

Formula: C27H28F3N7O3

References: [1]Walter AO, et al. Discovery of a mutant-selective covalent inhibitor of EGFR that overcomes T790M-mediated resistance in NSCLC. Cancer Discov. 2013 Sep 25.

CAS Number: 1374640-70-6

Molecular Weight: 555.55

Compound Purity: 99.79

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C)

Target: EGFR

• SKU: MEXHY-15729-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15729-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK