ROCK inhibitor-2, CAS 1127308-52-4

Product Description: ROCK inhibitor-2 (compound 6) is a selective dual inhibitor of ROCK1 and ROCK2, with IC50 values of 160 nM and 21 nM, respectively. ROCK inhibitor-2 inhibits pMYPT1 with IC50 of 75 nM[1].

Applications: COVID-19-anti-virus

Formula: C21H20N2O2

References: [1]Hobson AD, et al. Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based DrugDesign. J Med Chem. 2018 Dec 27;61(24):11074-11100.

CAS Number: 1127308-52-4

Molecular Weight: 332.40

Compound Purity: 99.92

Research Area: Inflammation/Immunology; Cardiovascular Disease

Solubility: DMSO : 200 mg/mL (ultrasonic)

Target: ROCK

• SKU: MEXHY-119937-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-119937-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK