Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (2E)-3-phenyl-2-propen-1-yl 6-O-a-L-arabinofuranosyl-ß-D-glucopyranoside
Purity: ≥98%
Formula Markup: C20H28O10
Formula Weight: 428.43032
CAS Number: 84954-93-8
Notes: Rosarin is a glycoside that has been found in R. rosea and has anti-inflammatory and immune regulatory activities.{61711} It prevents LPS-induced increases in induced nitric oxide synthase (iNOS), TNF-α, IL-1β, and IL-6 levels in BV-2 microglia when used at concentrations of 10 and 50 µg/ml. Rosarin reduces LPS-induced nitric oxide (NO) production in BV-2 microglia. It inhibits the growth of Jurkat T cells induced by concanavalin A (Item No. 14951) or anti-CD3 and anti-CD28 antibodies (IC50s = 60 and 68 µM, respectively) and increases TRAIL levels in isolated mouse splenic T cells when used at concentrations of 0.5, 5, and 50 µM.{61712}
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