Rosuvastatin, CAS 287714-41-4

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 7-[4-(4-fluorophenyl)-6E-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3R,5S-dihydroxy-6-heptenoic acid

Purity: ≥98%

Formula Markup: C22H28FN3O6S

Formula Weight: 481.5

CAS Number: 287714-41-4

Notes: Rosuvastatin is an inhibitor of HMG-CoA reductase (IC50 = 5 nM).{15309} It inhibits cholesterol synthesis in isolated rat hepatocytes with an IC50 value of 0.16 nM.{58863} Rosuvastatin (10 mg/kg) reduces plasma total cholesterol, triglyceride, LDL-C, and oxidized LDL-C levels in Ldlr-/- mice fed a high-fat diet.{58864} It decreases the area of aortic atherosclerotic lesions in the same model. Formulations containing rosuvastatin have been used in the treatment of dyslipidemias.

• SKU: CAY12029-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 12029-100
• Package Unit: 100 mg
• Quantity Unit: STK