RS-1, CAS 312756-74-4

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-bromo-N-(4-bromophenyl)-3-[[(phenylmethyl)amino]sulfonyl]-benzamide

Purity: ≥95%

Formula Markup: C20H16Br2N2O3S

Formula Weight: 524.2

CAS Number: 312756-74-4

Notes: RS-1 is an activator of DNA repair protein RAD51 (Kd = 48-107 for human RAD51 with different cofactors present).{32860} It stimulates homologous strand assimilation activity at least 5- to 11-old, enhancing homologous recombination activity of hRAD51.{32860} RS-1 is a potent enhancer of CRISPR-mediated genome editing, increasing homology directed repair 3- to 6-fold.{32862} It is used to increase CRISPR-mediated knock-in efficiencies in vitro and in vivo.{32862,32861,32863}

• SKU: CAY21037-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21037-50
• Package Unit: 50 mg
• Quantity Unit: STK