(RS)-4CPG, CAS 7292-81-1

Product Description: (RS)-4CPG ((RS)-4-Carboxyphenylglycine) is a type I metabotropic glutamate receptor antagonist with activity in blocking LTP induction. In mice lacking IP3R1, (RS)-4CPG (500μM) nearly blocked long-term potentiation (LTP) induced by type I metabotropic glutamate receptor activation, with LTP of 117.6±1.7% (n = 8) in IP3R1(-/-) mice and 116.9±1.8% (n = 5) in IP3R1(+/+) mice.

Applications: Neuroscience-Neuromodulation

Formula: C9H9NO4

References: [1]Neuronal plasticity in hippocampal mossy fiber-CA3 synapses of mice lacking the inositol-1,4,5-trisphosphate type 1 receptor

CAS Number: 7292-81-1

Molecular Weight: 195.17

Research Area: Others

Target: mGluR

• SKU: MEXHY-100617A-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100617A-1
• Package Unit: 1 mg
• Quantity Unit: STK