Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 3-hydroxy-1-methoxy-2-methyl-9,10-anthracenedione
Purity: ≥98%
Formula Markup: C16H12O4
Formula Weight: 268.26408
CAS Number: 7460-43-7
Notes: Rubiadin-1 methyl ether is an anthraquinone that has been found in Heterophyllaea pustulata and has diverse biological activities.{60908,60909,60910,60911} It generates superoxide radicals in isolated human neutrophils and monocytes when used at a concentration of 20 µg/ml, an effect that can be enhanced by UV radiation.{60908} Rubiadin-1 methyl ether (0.1, 1, and 10 µM) inhibits M-CSF- and RANKL-induced differentiation of osteoclasts.{60909} It inhibits C. tropicalis biofilm formation (MIC = 31.3 µg/ml for a clinical isolate).{60910} Rubiadin-1 methyl ether (30 mg/kg) reduces LPS-induced increases in bronchoalveolar fluid (BALF) levels of TNF-α, IL-6, and IFN-γ in a mouse model of acute lung injury.{60911}
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