Rubratoxin A, CAS 22467-31-8

Shelf life (days): 1460.0

Formulation: A powder

Formal Name: (4S,5R,10R)-rel-10-[(R)-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-[(1S)-1-hydroxyheptyl]-1H-cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione

Purity: ≥95%

Formula Markup: C26H32O11

Formula Weight: 520.5

CAS Number: 22467-31-8

Notes: Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A; IC50 = 170 nM).{31275} It has no significant effect on several other phosphatases, including PP1, PP2B, and protein tyrosine phosphatase 1B. Rubratoxin A drives overphosphorylation of PP2A substrate proteins in cultured cells treated for three hours at 20 µM.{31275} It causes suppression of tumor metastasis and reduction of primary tumor volume in mouse xenografts.{31275}

• SKU: CAY19605-250
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 19605-250
• Package Unit: 250 µg
• Quantity Unit: STK