Rucaparib phosphate, CAS 459868-92-9

PARP Inhibitor

CAS No.: 459868-92-9.

Molecular Formula: C19H18FN3O * H3PO4.

Molecular Weight: 421,4.

Source: Synthetic.

Purity: >98% (HPLC); NMR (Conforms).

Solubility: May be dissolved in DMSO (25 mg/ml).

Appearance: Yellow powder.

PubChem CID: 9931953.

Scientific Background: Rucaparib is a PARP1, PARP2 and PARP3 inhibitor and inhibits PARP-mediated DNA repair (1). It is being developed for ovarian, prostate and bladder cancers (2, 3).

References: 1. https://pubchem.ncbi.nlm.nih.gov/compound/rucaparib 2. Dockery L.E., Gunderson C.C., and Moore K.N. (2017) Onco Target Ther. 10: 3029-3037. 3. Syed Y.Y. (2017) Drugs. 77(5): 585-592.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-580-25MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-580-25MG
• Package Unit: 25 mg
• Quantity Unit: STK