Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 3-[[6-O-(6-deoxy-a-L-mannopyranosyl)-ß-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one, trihydrate
Purity: ≥98%
Formula Markup: C27H30O16 / 3H2O
Formula Weight: 664.6
CAS Number: 250249-75-3
Notes: Rutin is a flavonoid glycoside that has been found in buckwheat and has diverse biological activities.{30137,31793,16519,31794,31795} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) and ABTS (Item No. 27317) radicals when used at a concentration of 163.79 µM, as well as inhibits iron autoxidation, in cell-free assays.{30137,31793} Dietary administration of rutin (0.2% w/v) reduces tumor growth and the number of lung metastases in a B16/F10 murine melanoma model.{16519} Rutin (50 and 100 mg/kg) decreases intestinal acidity, increases intestinal activity of superoxide dismutase (SOD) and catalase, and reduces intestinal levels of protein carbonyls and thiobarbituric acid reactive substances (TBARS) formation in a rat model of intestinal toxicity induced by methotrexate (Item No. 13960).{31794} It also increases the time spent exploring the novel object in the novel object recognition (NOR) test and increases recognition and discriminative indices in a rat model of short-term episodic memory deficits induced by scopolamine (Item No. 14108).{31795}
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