Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: L-?-glutamyl-S-acetyl-L-cysteinyl-glycine
Purity: ≥98%
Formula Markup: C12H19N3O7S
Formula Weight: 349.36128
CAS Number: 3054-47-5
Notes: S-Acetyl-L-glutathione is a derivative of glutathione (GSH; Item No. 10007461).{46706} It is more stable in plasma than GSH and, unlike GSH, can be taken up into cells, where it is converted to GSH by intracellular thioesterases.{46706,46708,57054} S-Acetyl-L-glutathione (50 μM) increases intracellular GSH levels in primary fibroblasts derived from patients with glutathione synthetase deficiency.{46706} It induces apoptosis in Daudi, Raji, and Jurkat lymphoma cells when used at a concentration of 5 mM.{46707} It inhibits the replication of herpes simplex virus 1 (HSV-1) in human foreskin fibroblasts when used at concentrations of 5 and 10 mM.{46708} S-Acetyl-L-glutathione (6.25 μg/g per day), but not GSH, increases survival in a mouse model of HSV-1 infection.
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