(S)-p38 MAPK Inhibitor III, CAS 581098-48-8

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-[5-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-4-yl]-N-[(1S)-1-phenylethyl]-2-pyridinamine

Purity: ≥98%

Formula Markup: C23H21FN4S

Formula Weight: 404.5

CAS Number: 581098-48-8

Notes: (S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 µM in vitro).{31846} It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 µM, respectively).{31846}

• SKU: CAY19696-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 19696-5
• Package Unit: 5 mg
• Quantity Unit: STK