Product Description: (S)-SNAP5114 is a selective GABA transport inhibitor, with IC50 values of 5 μM and 21 μM for hGAT-3 and rGAT-2, respectively. (S)-SNAP5114 is an anticonvulsant agent[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C30H35NO6
References: [1]Borden LA, et al. Cloning of the human homologue of the GABA transporter GAT-3 and identification of a novel inhibitor with selectivity for this site. Receptors Channels. 1994;2(3):207-13./[2]Borden LA, et al. GABA transporter heterogeneity: pharmacology and cellular localization. Neurochem Int. 1996 Oct;29(4):335-56.
CAS Number: 157604-55-2
Molecular Weight: 505.60
Compound Purity: 98.16
Research Area: Neurological Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: GABA Receptor