Sabeluzole (Standard), CAS 104383-17-7

Sabeluzole (Standard), CAS 104383-17-7
SKU
MEXHY-105022R-0
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MedChemExpress

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Product Description: Sabeluzole (Standard) is the analytical standard of Sabeluzole. This product is intended for research and analytical applications. Sabeluzole (R 58735), a benzothiazol derivative, has antiischemic, antiepileptic, and cognitive-enhancing properties. Sabeluzole protects rat hippocampal neurons against NMDA- and glutamate-induced neurotoxicity via preventing tau expression. Sabeluzole enhances memory in rats, and prevents the amnesic effect of Chlordiazepoxide. Sabeluzole can be used fro research of Alzheimer's disease[1][2].

Formula: C22H26FN3O2S

References: [1]Hlinák Z,et al. Sabeluzole improves social recognition and antagonizes chlordiazepoxide's effect on habituation in the rat. Psychopharmacology (Berl). 1991;104(4):505-9. /[2]Uberti D, et al. Priming of cultured neurons with sabeluzole results in long-lasting inhibition of neurotoxin-induced tau expression and cell death. Synapse. 1997 Jun;26(2):95-103.

CAS Number: 104383-17-7

Molecular Weight: 415.52

Research Area: Neurological Disease

Target: Reference Standards;Tau Protein
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SKU MEXHY-105022R-0
Manufacturer MedChemExpress
Manufacturer SKU HY-105022R-0
Package Unit Get quote
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