Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 6-hydroxy-benzoic-2,3,4,5-d4 acid
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C7H2D4O3
Formula Weight: 142.14498
CAS Number: 78646-17-0
Notes: Salicylic acid-d4 is intended for use as an internal standard for the quantification of salicylic acid by GC- or LC-MS. Salicylic acid is an active metabolite of the COX inhibitor aspirin (Item No. 70260) and a plant hormone that has been found in Cucumis sativus.{59754,4728} It protects Cucumis sativus leaves from infection by S. fuliginea or E. cichoracearum when used at a concentration of 10 mM, as well as inhibits A. thaliana root growth at 0.3 mM.{4728,32819} Salicylic acid (1 and 4 mM) reduces IFN-γ- and TNF-α-induced increases in NOS2 expression in primary rat cardiac fibroblasts.{3736} It decreases urine prostaglandin E2 (PGE2; Item No. 14010) levels in dogs when administered at a dose of 40 mg/kg.{57913}