Sancycline (hydrochloride), CAS 6625-20-3

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: (4S,4aS,5aR,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide, monohydrochloride

Purity: ≥95%

Formula Markup: C21H22N2O7 / HCl

Formula Weight: 450.8693

CAS Number: 6625-20-3

Notes: Sancycline is a semisynthetic tetracycline antibiotic that is more active than tetracycline (Item No. 14328) against 339 strains of anaerobic bacteria (average MIC90s = 1 and 32 μg/ml, respectively).{41112,41113} Sancycline is active against tetracycline-resistant E. coli, S. aureus, and E. faecalis strains with MICs ranging from 0.06 to 1 μg/ml.{41114} In vivo, sancycline is active against S. aureus in mice with ED50 values of 0.46 and 0.6 mg/kg for intravenous and subcutaneous administration, respectively.

• SKU: CAY28118-250
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 28118-250
• Package Unit: 250 mg
• Quantity Unit: STK