Sapropterin (dihydrochloride), CAS 69056-38-8

Product Description: Sapropterin ((6R)-BH4) is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin also drives autoimmunity. Sapropterin can be used in study of phenylketonuria (PKU)[1][2].

Applications: COVID-19-immunoregulation

Formula: C9H17Cl2N5O3

References: [1]Sanford M, et al. Sapropterin: a review of its use in the treatment of primary hyperphenylalaninaemia. Drugs. 2009;69(4):461-76. /[2]Schmitz K, et al. Sapropterin (BH4) Aggravates Autoimmune Encephalomyelitis in Mice. Neurotherapeutics. 2021 Jul;18(3):1862-1879.

CAS Number: 69056-38-8

Molecular Weight: 314.17

Compound Purity: 99.87

Research Area: Metabolic Disease; Inflammation/Immunology

Solubility: DMSO : ≥ 200 mg/mL/H2O : 100 mg/mL (ultrasonic)

Target: Endogenous Metabolite

• SKU: MEXHY-A0124A-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-A0124A-25
• Package Unit: 25 mg
• Quantity Unit: STK