Product Description: SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM. SAR131675 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Applications: Cancer-Kinase/protease
Formula: C18H22N4O4
References: [1]Alam A, et al. SAR131675, a potent and selective VEGFR-3-TK inhibitor with antilymphangiogenic, antitumoral, and antimetastatic activities. Mol Cancer Ther. 2012 Aug;11(8):1637-49./[2]Paillasse MR, Esquerré M, Bertrand FA, et al. Targeting Tumor Angiogenesis with the Selective VEGFR-3 Inhibitor EVT801 in Combination with Cancer Immunotherapy. Cancer Res Commun. 2022;2(11):1504-1519.
CAS Number: 1433953-83-3
Molecular Weight: 358.39
Compound Purity: 99.76
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Target: VEGFR
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