SB 204990, CAS 154566-12-8

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: (3R,5S)-rel-5-[6-(2,4-dichlorophenyl)hexyl]tetrahydro-3-hydroxy-2-oxo-3-furanacetic acid

Purity: ≥95%

Formula Markup: C18H22Cl2O5

Formula Weight: 389.3

CAS Number: 154566-12-8

Notes: SB 204990 is a cell-permeable prodrug form of SB 201076, an inhibitor of ATP citrate lyase.{37244} SB 204990 inhibits fatty acid and cholesterol synthesis in HepG2 cells in a concentration-dependent manner. Oral administration of SB 204990 (25 mg/kg) reduces plasma levels of the lipoproteins VLDL, LDL, and HDL by 21, 40, and 22%, respectively, in dogs. It also reduces VLDL synthesis and plasma cholesterol and triglyceride levels in rats in a dose-dependent manner.

• SKU: CAY15245-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 15245-5
• Package Unit: 5 mg
• Quantity Unit: STK