Shelf life (days): 1460
Info: A nonpeptide αVβ3 and αVβ5 integrin antagonist (Kis =1.2 and 0.3 nM, respectively); reduces paw edema and increases bone density in a rat model of adjuvant-induced arthritis at 30 and 60 mg/kg; reduces the number of Th2 cells and production of IL-10 in pregnant mice at 3 mg/kg
Formulation: A solid
Formal Name: 2,3,4S,5-tetrahydro-8-[2-[6-(methylamino)-2-pyridinyl]ethoxy]-3-oxo-2-(2,2,2-trifluoroethyl)-1H-2-benzazepine-4-acetic acid
Purity: ≥98%
Formula Markup: C22H24F3N3O4
Formula Weight: 451.438989
CAS Number: 205678-31-5