SBI-810 (hydrochloride), CAS 2772746-58-2

Product Description: SBI-810 hydrochloride is a functionally selected β-arrestin-biased neurotensin receptor 1 (NTSR1) allosteric modulator. SBI-810 hydrochloride modulates NTSR1 G protein signaling in a G protein-specific manner in the presence of the endogenous ligand, neurotensin (NT). SBI-810 hydrochloride fully antagonizes NT-induced activation of Gq, partially antagonizes NT-induced activation of Gi1 and is permissive of NTSR1 activation of GoA and G12[1][2].

Formula: C27H35ClN4O2

References: [1]Lawrence Barak, et al. Compositions for and methods of treating and/or preventing pain. WO2022241186A1. 2022 November 17./[2]Center M N A, et al. Summer Undergraduate Research Expo[J]. 2014.

CAS Number: 2772746-58-2

Molecular Weight: 483.05

Compound Purity: 99.11

Research Area: Neurological Disease

Target: Neurotensin Receptor

• SKU: MEXHY-164795A-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-164795A-5
• Package Unit: 5 mg
• Quantity Unit: STK