SC-236, CAS 170569-86-5

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide

Purity: ≥98%

Formula Markup: C16H11ClF3N3O2S

Formula Weight: 401.8

CAS Number: 170569-86-5

Notes: The physiologic roles and importance of constitutive COX-1 and inducible COX-2 have been reviewed.{11295,10878} SC-236 is a potent, selective, orally active inhibitor of COX-2 with an IC50 of 10 nM and approximately 18,000-fold COX-2 selectivity.{12282} SC-236 has a long plasma half-life and can be dosed once daily (20 mg/kg) in rodents to achieve lasting inhibition of COX-2.{11450}

• SKU: CAY10004219-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 10004219-5
• Package Unit: 5 mg
• Quantity Unit: STK