SCFSkp2-IN-2, CAS 1375060-02-8

Product Description: SCFSkp2-IN-2 (Compound AAA-237) is a Skp2 inhibitor with a KD of 28.77 μM. AAA-237 induces apoptosis of NSCLC cells and shows antitumor activities[1].

Applications: Cancer-programmed cell death

Formula: C17H20N4O2

References: [1]Liu J, et al. Anti-tumor effects of Skp2 inhibitor AAA-237 on NSCLC by arresting cell cycle at G0/G1 phase and inducing senescence. Pharmacol Res. 2022 Jul;181:106259.

CAS Number: 1375060-02-8

Molecular Weight: 312.37

Compound Purity: 99.44

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C)

Target: E1/E2/E3 Enzyme

• SKU: MEXHY-148900-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-148900-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK