SCH 28080, CAS 76081-98-6

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2-methyl-8-(phenylmethoxy)-imidazo[1,2-a]pyridine-3-acetonitrile

Purity: ≥98%

Formula Markup: C17H15N3O

Formula Weight: 277.3

CAS Number: 76081-98-6

Notes: SCH 28080 is a reversible K+-competitive inhibitor of H+/K+-ATPases that is best known for its ability to block acid secretion through its action against the gastric H+/K+-ATPase (IC50 = 1.3 µM).{29478,29482,29481} It is effective against gastric H+/K+-ATPases from a variety of species and can inhibit colonic H+/K+-ATPases, but this activity appears to be species-dependent.{29480} SCH 28080 is also used to investigate the role of H+/K+-ATPases in non-mammalian organisms and to distinguish the actions of H+/K+-ATPases from other ATP-dependent transporters.{29477,29479}

• SKU: CAY17885-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 17885-50
• Package Unit: 50 mg
• Quantity Unit: STK