SD 0006, CAS 271576-80-8

Product Description: SD 0006 (SD-06) is an orally active, selective, ATP-competitive and potent diaryl pyrazole inhibitor of p38α MAP kinase, with an IC50 of 110 nM for p38α[1][2].

Applications: COVID-19-immunoregulation

Formula: C20H20ClN5O2

References: [1]Burnette BL, et al. SD0006: a potent, selective and orally available inhibitor of p38 kinase. Pharmacology. 2009;84(1):42-60./[2]Walker JK, et al. Identification of SD-0006, a potent diaryl pyrazole inhibitor of p38 MAP kinase. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2634-8.

CAS Number: 271576-80-8

Molecular Weight: 397.86

Compound Purity: 98.73

Research Area: Inflammation/Immunology

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Autophagy;p38 MAPK

• SKU: MEXHY-11087-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-11087-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK