SD-1029, CAS 118372-34-2

Product Description: SD-1029 is a JAK2/STAT3 inhibitor[1]. SD-1029 inhibits STAT3 nuclear translocation. SD-1029 is an inhibitor of STAT3 activation due to inhibition of JAK2 phosphorylation[2].

Applications: Cancer-Kinase/protease

Formula: C25H32Br2Cl2N2O3

References: [1]Zhenfeng Duan, et al. SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation. Clin Cancer Res. 2006 Nov 15;12(22):6844-52./[2]Nor Fazila Che Mat, et al. Interleukin-23-induced interleukin-23 receptor subunit expression is mediated by the Janus kinase/signal transducer and activation of transcription pathway in human CD4 T cells. J Interferon Cytokine Res. 2011 Apr;31(4):363-71.

CAS Number: 118372-34-2

Molecular Weight: 639.25

Compound Purity: 88.8

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: JAK;STAT

• SKU: MEXHY-112391-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-112391-1
• Package Unit: 1 mg
• Quantity Unit: STK