SD-169, CAS 1670-87-7

Product Description: SD-169 is an orally active ATP-competitive inhibitor of p38α MAPK, with an IC50 of 3.2 nM. SD-169 also weakly inhibits p38β MAPK with an IC50 of 122 nM. SD-169 prevents the development and progression of diabetes by inhibiting T cell infiltration and activation[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C9H8N2O

References: [1]Medicherla S, et al. Preventive and therapeutic potential of p38 alpha-selective mitogen-activated protein kinase inhibitor in nonobese diabetic mice with type 1 diabetes. J Pharmacol Exp Ther. 2006 Jul;318(1):99-107.

CAS Number: 1670-87-7

Molecular Weight: 160.176

Compound Purity: 99.91

Research Area: Metabolic Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: p38 MAPK

• SKU: MEXHY-W015445-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W015445-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK