SDF-1 beta/CXCL12, Human (HEK293, Fc)

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Product Description: SDF-1 beta (Stromal-derived factor-1β, SDF-1β) is a stromal derived CXC chemokine that signal through the CXCR4 receptor. SDF-1β has chemotactic activity on B and T cells[1][2]. SDF-1 beta/CXCL12 Protein, Human (HEK293, Fc) is produced in HEK293 cells with a N-Terminal Fc-tag. It consists of 72 amino acids (K22-M93).

Formula: 6387(Gene_ID)P48061-1 (K22-M93)(Accession)

References: [1]Maria De La Luz Sierra, et al. Differential processing of stromal-derived factor-1alpha and stromal-derived factor-1beta explains functional diversity. Blood. 2004 Apr 1;103(7):2452-9./[2]Zheng Jiang, et al. Contribution of SDF-1α/CXCR4 signaling to brain development and glioma progression. Neurosignals. 2013;21(3-4):240-58./[3]Miroslaw Janowski. Functional diversity of SDF-1 splicing variants. Cell Adh Migr. 2009 Jul-Sep;3(3):243-9./[4]Kleanthis Fytianos, et al. Anti-Fibrotic Effect of SDF-1β Overexpression in Bleomycin-Injured Rat Lung. Pharmaceutics. 2022 Aug 27;14(9):1803.

Molecular Weight: Approximately 38-42 kDa due to the glycosylation.

Compound Purity: 95.00

• SKU: MEXHY-P73411-2UG
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P73411-2UG
• Package Unit: 2 μg
• Quantity Unit: STK