Product Description: Setmelanotide (monoacetate) is a melanocortin 4 receptor (MC4R) agonist that acts on human and rat MC4R with EC50 values of 0.27 nM and 0.28 nM, respectively[1][2].
Formula: C51H72N18O11S2
References: [1]Kumar KG, et al. Analysis of the therapeutic functions of novel melanocortin receptor agonists in MC3R- and MC4R-deficient C57BL/6J mice. Peptides. 2009 Oct;30(10):1892-900./[2]Kievit P, et al. Chronic treatment with a melanocortin-4 receptor agonist causes weight loss, reduces resistance, and improves cardiovascular function in diet-induced obese rhesus macaques. Diabetes. 2013 Feb;62(2):490-7.
CAS Number: 2759937-80-7
Molecular Weight: 1177.36
Compound Purity: 99.71
Research Area: Endocrinology; Metabolic Disease
Target: Melanocortin Receptor