SGC707, CAS 1687736-54-4

Product Description: SGC707 is a potent, selective, and non-competitive PRMT3 (protein arginine methyltransferase 3) inhibitor (IC50=31 nM, Kd=53 nM).

Applications: Cancer-programmed cell death

Formula: C16H18N4O2

References: [1]Kaniskan HÜ, et al. A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3). Angew Chem Int Ed Engl. 2015 Apr 20;54(17):5166-70./[2]de Jong LM, et al. PRMT3 inhibitor SGC707 reduces triglyceride levels and induces pruritus in Western-type diet-fed LDL receptor knockout mice. Sci Rep. 2022 Jan 10;12(1):483.

CAS Number: 1687736-54-4

Molecular Weight: 298.34

Compound Purity: 98.08

Research Area: Metabolic Disease

Solubility: DMSO : ≥ 100 mg/mL

Target: Histone Methyltransferase

• SKU: MEXHY-19715-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-19715-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK