Product Description: SGX523 is a exquisitely selective and ATP-competitive MET inhibitor. SGX523 potently inhibits MET with an IC50 of 4 nM and is >1,000-fold selective versus other protein kinases. Antitumor activity[1].
Applications: Cancer-Kinase/protease
Formula: C18H13N7S
References: [1]Buchanan SG, et al. SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo. Mol Cancer Ther, 2009, 8(12), 3181-3190.
CAS Number: 1022150-57-7
Molecular Weight: 359.41
Compound Purity: 99.0
Research Area: Cancer
Solubility: DMSO : 30 mg/mL (ultrasonic)
Target: c-Met/HGFR