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Product Description: Siglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-hFc labeled tag.SKU | MEXHY-P73640-10UG |
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Manufacturer | MedChemExpress |
Manufacturer SKU | HY-P73640-10UG |
Package Unit | 10 μg |
Quantity Unit | STK |
Product information (PDF) |
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MSDS (PDF) |
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