Product Description: Sirtratumab vedotin (ASG15-ME) is an ADC composed of a SLITRK6-specific human gamma 2 antibody (Igγ2) conjugated to a small molecule microtubule disrupting agent, monomethyl auristatin E (MMAE) via a protease-cleavable linker[1].
Formula: N/A
References: [1]Morrison K, et al. Development of ASG-15ME, a Novel Antibody-Drug Conjugate Targeting SLITRK6, a New Urothelial Cancer Biomarker. Mol Cancer Ther. 2016 Jun;15(6):1301-10.
CAS Number: 1824663-83-3
Molecular Weight: N/A
Research Area: Cancer
Solubility: H2O
Target: Antibody-Drug Conjugates (ADCs)