SKA-31, CAS 40172-65-4

KCa3.1 and KCa2 channel activator

CAS No.: 40172-65-4.

Molecular Formula: C11H8N2S.

Molecular Weight: 200,1.

Source: Synthetic.

Purity: >98% (TLC); NMR (Conforms).

Solubility: May be dissolved in DMSO (40mg/ml).

Appearance: Off-white powder.

PubChem CID: 94880.

Scientific Background: SKA 31 is an activator of KCa3.1 and KCa2 channels. It has significant blood-pressure reducing activity in experimentally hypertensive mice, suggesting potassium channel activation as a therapeutic target for hypertension.

References: 1. Sankaranarayanan A., et al. (2009) Mol Pharmacol. 75 (2): 281-295.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-595-10MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-595-10MG
• Package Unit: 10 mg
• Quantity Unit: STK