SKL1223

Shelf life (days): 1460

Info: A TXNIP inhibitor; inhibits TXNIP promoter activity in a reporter assay using INS-1 cells expressing human TXNIP (IC50 = 0.64 µM); decreases the levels of TXNIP in the same cells in a concentration-dependent manner; induces glucagon secretion from TC-1 mouse lung cancer cells and decreases glucagon-induced glucose production in primary mouse hepatocytes; decreases fasting blood levels of glucose, serum levels of glucagon and triglycerides, and hepatic levels of triglycerides in mice at 70 mg/kg per day; decreases blood levels of glucose and serum levels of glucagon in db/db mice but not in Txnip-/- mice

Formulation: A solid

Formal Name: N-(furan-2-ylmethyl)-4-(3-phenyl-1,2,4-oxadiazol-5-yl)aniline

Purity: ≥98%

Formula Markup: C19H15N3O2

Formula Weight: 317.348

• SKU: CAY42952-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42952-1
• Package Unit: 1 mg
• Quantity Unit: STK