SKLB-23bb, CAS 1815580-06-3

Product Description: SKLB-23bb is a potent and selective inhibitor for HDAC6 with an IC50 of 17 nM and shows 25-fold and 200-fold selectivity relative to HDAC1 (IC50=422 nM) and HDAC8 (IC50=3398 nM), respectively.

Applications: Cancer-programmed cell death

Formula: C21H24N4O4

References: [1]Yang Z, et al. Discovery of Selective Histone Deacetylase 6 Inhibitors Using the Quinazoline as the Cap for the Treatment of Cancer. J Med Chem. 2016 Feb 25;59(4):1455-70.

CAS Number: 1815580-06-3

Molecular Weight: 396.44

Compound Purity: 98.0

Research Area: Cancer

Solubility: DMSO : 32 mg/mL (ultrasonic;warming)

Target: HDAC

• SKU: MEXHY-18947-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-18947-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK