Product Description: SLV310 is an orally active dopamine D2 receptor antagonist (Ki: 5 nM) and serotonin reuptake receptor inhibitor. SLV310 antagonizes Apomorphine (HY-12723) induced climbing behaviour and 5-HTP (HY-N0122) induced serotonin syndrome like behaviour in mice (ED50: 5.6 and 5.9 mg/kg, p.o.). SLV310 is an antipsychotic compound and can be used for schizophrenia research[1].
Applications: Neuroscience-Neuromodulation
Formula: C25H24FN3O2
References: [1]van Hes R,et al. SLV310, a novel, potential antipsychotic, combining potent dopamine D2 receptor antagonism with serotonin reuptake inhibition. Bioorg Med Chem Lett. 2003 Feb 10;13(3):405-8.
CAS Number: 264869-71-8
Molecular Weight: 417.48
Research Area: Neurological Disease
Target: Dopamine Receptor;Serotonin Transporter