SMIP004, CAS 143360-00-3

Product Description: SMIP004 is a SKP2 E3 ligase inhibitor, which downregulates SKP2 and to stabilise p27. SMIP004 is a cancer cell selective apoptosis inducer of human prostate cancer cells[1][2].

Applications: Cancer-Kinase/protease

Formula: C13H19NO

References: [1]Li C, et al. SKP2 promotes breast cancer tumorigenesis and radiation tolerance through PDCD4 ubiquitination. J Exp Clin Cancer Res. 2019 Feb 13;38(1):76./[2]Rico-Bautista E, Zhu W, Kitada S, Small Molecule-Induced Mitochondrial Disruption Directs Prostate Cancer Inhibition via UPR Signaling. Oncotarget. 2013 Jul 14.

CAS Number: 143360-00-3

Molecular Weight: 205.30

Compound Purity: 98.46

Research Area: Cancer

Solubility: DMSO : ≥ 100 mg/mL

Target: Apoptosis;E1/E2/E3 Enzyme

• SKU: MEXHY-15694-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15694-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK