SMU-CX1, CAS 10371-86-5

Product Description: SMU-CX1 is a specific TLR3 inhibitor (IC50: 0.11 μM) with IC50 ranging from 0.14-0.33 μM against multiple influenza A virus subtypes. SMU-CX1 inhibits the viral PB2 and NP proteins with an IC50 of 0.43 μM for SARS-CoV-2 activity. SMU-CX1 also inhibits inflammatory factors in host cells, including IFN-β, IP-10, and CCL-5[1].

Applications: COVID-19-anti-virus

Formula: C18H16N2O

References: [1]Pan Y, et al. Discovery of an ellipticine derivative as TLR3 inhibitor against influenza A virus and SARS-CoV-2. Bioorg Med Chem Lett. 2024 Mar 15;101:129672.

CAS Number: 10371-86-5

Molecular Weight: 276.33

Research Area: infection

Solubility: 10 mM in DMSO

Target: SARS-CoV;Toll-like Receptor (TLR)

• SKU: MEXHY-N12110-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N12110-5
• Package Unit: 5 mg
• Quantity Unit: STK