Product Description: SN 2 is a potent activator of TRPML3 ion channel with an EC50 of 1.8 μM[1]. SN 2 also acts as a potent inhibitor of Dengue virus 2 (DENV2) and Zika virus (ZIKV)[2].
Formula: C17H21NO
References: [1]Grimm C, et al. Small molecule activators of TRPML3. Chem Biol. 2010 Feb 26;17(2):135-48./[2]Zhiqiang Xia, et al. ML-SA1, a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity. Antiviral Res. 2020 Aug 26;104922.
CAS Number: 823218-99-1
Molecular Weight: 255.35
Compound Purity: 99.16
Research Area: Infection
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Dengue virus;Flavivirus;TRP Channel