SNS-314 (mesylate), CAS 1146618-41-8

Product Description: SNS-314 mesylate is a potent and selective aurora kinase inhibitor with IC50s of 9, 31, and 6 nM for aurora A, B and C, respectively[1].

Applications: Cancer-Kinase/protease

Formula: C19H19ClN6O4S3

References: [1]Oslob JD, et al. Discovery of a potent and selective aurora kinase inhibitor. Bioorg Med Chem Lett. 2008 Sep 1;18(17):4880-4./[2]Arbitrario JP, et al. SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and dosing flexibility in vivo. Cancer Chemother Pharmacol. 2010 Mar;65(4):707-17.

CAS Number: 1146618-41-8

Molecular Weight: 527.04

Compound Purity: 99.53

Research Area: Cancer

Solubility: DMSO : 150 mg/mL (ultrasonic)

Target: Aurora Kinase

• SKU: MEXHY-12003-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12003-5
• Package Unit: 5 mg
• Quantity Unit: STK