Target Synonym: SNX19;CHET8
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: Islet antigen-2 (IA-2) is an autoantigen in type 1 diabetes and plays a role in insulin secretion. IA-2 is found in dense-core secretory vesicles and interacts with the product of this gene, a sorting nexin. In mouse pancreatic beta-cells, the encoded protein influenced insulin secretion by stabilizing the number of dense-core secretory vesicles.
Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Immunogen: Recombinant fusion protein of human SNX19
Dilution: WB 1:500-1:2000
Calculated MW: 87kDa/108kDa
Observed MW: 108kDa