Shelf life (days): 1460.0
Formulation: A solid
Formal Name: benzene-d5-butanoic-d6 acid, monosodium salt
Purity: ≥99% deuterated forms (d1-d11)
Formula Markup: C10D11O2 / Na
Formula Weight: 197.24957
CAS Number: 1392208-11-5
Notes: Sodium 4-Phenylbutyrate-d11 is intended for use as an internal standard for the quantification of sodium 4-phenylbutyrate (Item No. 11323) by GC- or LC-MS. Sodium 4-phenylbutyrate is a chemical chaperone that has been shown to rescue the trafficking of misfolded proteins.{23406,23405} It also weakly blocks histone deacetylase activity (IC50 = 0.4 mM), which results in cell cycle arrest, differentiation, and/or apoptosis of various tumors.{17643,23404} Formulations containing sodium 4-phenylbutyrate have been used for the treatment of urea cycle disorders.