Shelf life (days): 1460.0
Formulation: A powder
Formal Name: somatostatin, monoacetate
Purity: ≥98%
Formula Markup: C76H104N18O19S2 / C2H4O2
Formula Weight: 1697.9
CAS Number: 54472-66-1
Notes: Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin.{33263} It is a somatostatin (SST) receptor agonist that binds to SST1, SST2, SST3, SST4, and SST5 (IC50s = 0.22, 0.10, 0.28, 1.23, and 0.30 nM, respectively, in CCL39 cells expressing human recombinant receptors).{42022} It inhibits cAMP accumulation induced by forskolin (Item No. 11018) in CCL39 cells expressing human recombinant SST1, SST2, SST3, SST4, and SST5 (EC50s = 6.16, 4.37, 17.38, 2.95, and 4.67 nM, respectively).{42023} Somatostatin-14 inhibits the release of growth hormone, prolactin, thyrotropin, glucagon, and insulin, as well as other signaling molecules.{33263,5903,12953}