Sovleplenib, CAS 1415792-84-5

Product Description: Sovleplenib (HMPL-523) is a highly potent, orally available and selective SYK inhibitor with an IC50 of 25 nM. Anti-tumor activity. Sovleplenib can be used for the research of immune thrombocytopenia (ITP)[1].

Applications: Cancer-Kinase/protease

Formula: C24H30N6O3S

References: [1]Su WG, et al. Preparation of pyridopyrazine derivatives for use as Syk inhibitors. WO2012167733 A1./[2]Na Yang, et al. HMPL-523, a Novel SYK Inhibitor Showed Anti-Tumor Activities In Vitro and In Vivo. Blood (2016) 128 (22): 3970.

CAS Number: 1415792-84-5

Molecular Weight: 482.60

Compound Purity: 99.94

Research Area: Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Syk

• SKU: MEXHY-145598-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-145598-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK