Clone Name: HMV338
Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Specificity/Sensitivity: <b>Highly recommended for IHC-P in human tissues.</b>
Form: Liquid
Buffer (with preservative): PBS, 2% BSA, 20% Glycerol, 0.025% ProClin 300.
Concentration: 0.44 mg/ml
Background: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq]
Uniprot ID: P48431
Antigen Species: Human
Immunogen: Recombinant protein encompassing a sequence within the center region of human SOX2. The exact sequence is proprietary.
Purification: Affinity purified by Protein G.
Conjugation: Unconjugated
Full Name: SRY-box 2
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