Spermine, CAS 71-44-3

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N1,N4-bis(3-aminopropyl)-1,4-butanediamine

Purity: ≥95%

Formula Markup: C10H26N4

Formula Weight: 202.3

CAS Number: 71-44-3

Notes: Spermine is an endogenous polyamine synthesized from the reaction of spermidine (Item No. 14918) with decarboxylated S-adenosylmethionine in the presence of the enzyme spermine synthase and is required for eukaryotic cell growth and protein synthesis.{27553,29231} Intracellular spermine blocks inward rectifying K+ channels, whereas extracellular spermine acts as a mixed NMDA glutamate receptor agonist/antagonist at the polyamine site.{29232} Spermine has neuroprotective and anti-inflammatory effects and functions as a free radical scavenger to prevent DNA damage by reactive oxygen species.{29233}

• SKU: CAY18041-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 18041-10
• Package Unit: 10 g
• Quantity Unit: STK